Anadrol Increases Muscle Mass Reduces Fat But Damages The Liver

Anadrol Increases Muscle Mass Reduces Fat But Damages The Liver

Blog Entry #18

By Admin –

Anadrol, or Oxymethlolone, has been around since 1959 and was originally developed by Syntax to aid weight gain, the preservation of mass during diseases or treatments and other catabolic periods. It has long been known that Anadrol can aid muscle to ones frame but what else does it do?

An American study done in January 2003, by the University of Southern California, tested its effects on untrained healthy subjects. Elderly man aged between 65 and 80 were divided into three groups. One was given placebo, another 50mg Anadrol every day and the last groupd 100mg every day. No weight training was done, so the study was done on sedentary individuals, there subjects also consumed 1g per kg of bodyweight. If we put that into perspective, bodybuilders and athletes seeking more muscle mass consume 1-3x this in protein per pound of bodyweight, not kg. Thus bringing their total protein intake to 200-500g every day.

This study lasted for 12 weeks and the results from the Anadrol administering groups are fairly interesting. The 50mg Anadrol per day groups lean body mass increased by 3.3kg, whilst the 100mg Aandrol per day groups increased by 4.1kg.  The effects Oxymetholone had on fat mass were also recorded and the US researchers found fat mass in the two groups decreased by 2.6 and 2.5 kg respectively. That’s a fair amount of added muscle mass on individuals not training at all, elderly, a lot protein intake and a significant reduction on body fat levels. Its logical to assume these effects would be enhanced with a good training program, diet high in protein and cardiovascular routine daily.













The study goes a little further and explains where this fat mass was lost. In the 50mg group, subjects lost 1.7kg in the truck area or abdominal area.

Strength was measured in this well-rounded study as well. The most responsive exercises were chest-press, lat-pulldown and leg press exercises where the Oxymetholone group added 10-30% to their lifts.







Blood tests were carried out on the subjects, ranging from cholesterol levels to liver values. One male individual in the 100mg group experienced dangerously high ALT enzymes (liver values). Its common knowledge 17-alpha-alkylated oral anabolic steroids cause hepatic problems and this is why oral steroid usage is advised to be no more than 4-6 weeks without a break. However, after the US researchers questioned him, he admitted consuming four glasses of wine the night before the blood test was taken the following morning. After a week without any alcohol, his ALT enzymes returned to normal, which shows the damage even a low consumption of alcohol can do on oral steroid users. In both Anadrol groups AST and ALT levels rose slightly and the readings were statistically significant. Other side effects were that HDL (good cholesterol) dropped.

“The study leaves a number of issues unresolved, including the optimal formulation of androgen for supplementation in this age group, the benefits and risks of longer periods of therapy, the durability of outcomes associated with intermittent therapy, the question of whether measures of visceral adipose tissue and markers of atherosclerosis are improved, and the question of whether similar beneficial effects can be achieved in older women”, the US researchers write.

Limitations were mainly that these subjects were aged between 65 and 80 years old. The majority of you reading this aren’t. The test numbers were also fairly low testing only 31 males.


Am J Physiol Endocrinol Metab 2003 Jan;284(1):E120-8